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Antibacterial Activity of Copolymers of Trialkyl(4-vinylbenzyl)ammonium chlorides with acrylonitrile

M. Senuma, M. Iwakura, S. Ebihara, Y. Shimura, and K. Kaeriyama
[Angew. Makromol. Chem., Vol.204, p.119, 1993]


Homopolymers of cetyldimethyl(4-vinylbenzyl)ammonium chloride (VB16), lauryldimethyl(4-vinylbenzyl)ammonium chloride (VB12), and trimethyl(4-vinylbenzyl)ammonium chloride (VB1), and copolymers of these compounds with acrylonitrile were examined for antibacterial activity using B. subtilis, S. aureus (Fig.1), E. coli, and P. aeruginosa. All homopolymers and copolymers showed germicidal action to the bacterias, especially strong action to gram-positive B. subtilis and S. aureus. The strength of the germicidal action of the quaternary ammonium branches was in the order: VB16 ľ VB12 ľľ VB1.

Fig.1